I've been using Eyegreeable software programme with Windows 10. Due to my dyslexia I find it difficult to follow text on the computer screen, it is very easy to lose my place when reading, Eyegreeable has some amazing features . Another big problem is eye strain, this programme has features to help eliminate screen glare by tinting out parts of the computer screen, there are lots of different colours you can use. The programme is very simple to use, I like the way you can add static lines in different colours,  I use this  as a line marker. The programme interface is very easy to use, the program also supports dual monitors.
www.aureosoft.com/eyegreeable.html
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Eyegreeable
eyegreeable_videos.html
Please go to their website to have a look at all the features,  there is a video explaining   about this amazing tool.